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目的:探讨子宫内膜癌的临床特点及预后影响因素。方法:对42例子宫内膜癌患者的临床症状、临床分期、手术病理分期及治疗方法进行回顾性分析。结果:患者年龄为30~70岁,临床表现以绝经后阴道流血最多(57.1%),其次为绝经前月经量增多或不规则阴道流血(35.7%)、下腹部胀痛(21.4%);临床分期与手术病理分期符合率为71.48%,肌层浸润率高达85.7%,肌层浸润程度、手术病理分期、术后辅助治疗对预后有明显影响(P<0.05),组织学类型及病理分级对预后无明显影响(P>0.05)。结论:确定手术病理分期、肌层浸润深度、术后适当的辅助治疗(化疗、放疗)是改善子宫内膜癌预后的关键。
Objective: To investigate the clinical features and prognostic factors of endometrial cancer. Methods: The clinical symptoms, clinical stage, pathological staging and treatment of 42 cases of endometrial cancer were retrospectively analyzed. Results: The age of patients was 30-70 years old, the clinical manifestations were vaginal bleeding in postmenopausal women (57.1%), followed by premenopausal menorrhagia or irregular vaginal bleeding (35.7%) and lower abdominal pain (21.4%). Clinical The coincidence rate was 71.48% in staging and surgical staging, the myometrial invasion rate was as high as 85.7%, the degree of myometrial invasion, surgical pathological staging and postoperative adjuvant therapy had significant effects on prognosis (P <0.05), histological type and pathological grading No significant effect on prognosis (P> 0.05). Conclusion: It is the key to improve the prognosis of endometrial carcinoma by determining the pathological stage of operation, the depth of myometrial invasion and the appropriate adjuvant therapy (chemotherapy and radiotherapy) after operation.