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目的:观察奥美拉唑联用铝碳酸镁片治疗慢性消化性溃疡的效果,为临床治疗提供参考依据。方法:选取我院确诊的慢性消化性溃疡患者96例进行对比研究,随机分为对照组(n=48)和观察组(n=48),对照组给予奥美拉唑治疗,而观察组联用奥美拉唑和铝碳酸镁片治疗,对比两组患者的临床治疗效果。结果:对照组治疗总有效率为79.17%(38/48),而观察组为95.83%(46/48),临床治疗效果明显优于对照组,差异有统计学意义(P<0.05);对照组不良反应发生率为6.25%(3/48),而观察组为8.33%(4/48),两组无明显差异(X~2=0.154,P=0.695)。结论:奥美拉唑联用铝碳酸镁片治疗慢性消化性溃疡的效果较显著,且并不加重不良反应,可在临床治疗中推广应用。
Objective: To observe the effect of omeprazole combined with aluminum magnesium carbonate in the treatment of chronic peptic ulcer and provide a reference for clinical treatment. Methods: A total of 96 patients with chronic peptic ulcer diagnosed in our hospital were selected and randomly divided into control group (n = 48) and observation group (n = 48). The control group was treated with omeprazole, while the observation group Omeprazole and aluminum magnesium carbonate tablets were used to compare the clinical effects of the two groups. Results: The total effective rate of the control group was 79.17% (38/48), while that of the observation group was 95.83% (46/48). The clinical effect was better than that of the control group (P <0.05) The adverse reaction rate was 6.25% (3/48) in the observation group and 8.33% (4/48) in the observation group. There was no significant difference between the two groups (X ~ 2 = 0.154, P = 0.695). Conclusion: The combination of omeprazole and aluminum magnesium carbonate in the treatment of chronic peptic ulcer is more effective, and does not aggravate the adverse reactions. It can be widely used in clinical treatment.