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蛋白激酶G(PKG)在微血管通透性升高的细胞内信号转导中是一个重要的信号分子 ,其组成的Ca2 + NO cGMP PKG级联反应在微血管通透性的调节中起重要作用。PKG的作用底物有血管扩张剂刺激的磷蛋白(VASP)、热休克蛋白 2 7(HSP2 7)等
Protein kinase G (PKG) is an important signaling molecule in intracellular signal transduction with increased microvascular permeability and its cascade of Ca2 + NO cGMP PKG plays an important role in the regulation of microvascular permeability. The substrates of PKG are vasodilator-stimulated phosphoprotein (VASP), heat shock protein 27 (HSP27), etc.