本文报告8例SSPE,年龄9～23岁,临床表现以进行性行为改变、痴呆,局部或全身肌阵挛,最后常呈去大脑强直衰竭死亡。8例EEG改变较典型。CSF检查7例胶金曲线呈麻痹型,2例IgG增高。3例曾误诊为精神分裂症或散发性脑炎,故早期患者须与有关疾病鉴别。本组8例经一般治疗无效。随访6例,其中4例病后1～14个月死亡、仅1例至今九年半仍能作简单劳动、1例呈醒状昏迷。 This article reports 8 cases of SSPE, aged 9 to 23 years old, the clinical manifestations of behavioral changes, dementia, local or systemic myoclonus, and finally often went to brain tonic failure death. 8 cases of EEG changes more typical. 7 cases of CSF gold gel examination showed paralytic curve, 2 cases of IgG increased. Three cases had been misdiagnosed as schizophrenia or sporadic encephalitis, so early patients with the disease to be identified. The group of 8 patients treated by general invalid. Six patients were followed up, of which 4 died after 1 ~ 14 months and only 1 patient was still working for nine and a half years. One patient was awake unconscious.