论文部分内容阅读
C~(14)标記的醇类及卤代烷是合成C~(14)标記化合物的重要中間体,一般均由C~(14)标記的羧酸制备。麦耳推尔(D.B.Melville)等[’1用亚路酸铜作催化剂在常压、16。℃氢化还原甲酸一C14一甲醋制得甲醇一Cl‘.但用同样的催化剂还原乙酸乙醋需在一定压力下进行[2].也有报导将甲酸或乙酸制成编(镍)盐[恒eoo玉ed(Ni):(eH3eoo)Zed(Ni)]推用亚路酸铜作催化剂加压还原制得Cl毛标昆的甲醇或乙醇[
The alcohols labeled with C ~ (14) and alkyl halides are important intermediates for the synthesis of C ~ (14) labeled compounds and are usually prepared from C ~ (14) - labeled carboxylic acids. D.B.Melville et al [’1 with copper as catalyst in the atmospheric pressure, 16. ° C hydrogenation of a C14 a methyl acetate to obtain a methanol Cl ’, but with the same catalyst reduction of ethyl acetate need to be under certain pressure [2]. It has also been reported formic acid or acetic acid made of (nickel) salt [constant eoo jade ed (Ni): (eH3eoo) Zed (Ni)] push the use of copper as a catalyst for pressure reduction of Cl wool superscript Kun methanol or ethanol [