目的探讨前列腺影像报告和数据系统(PI-RADSv2)对外周带前列腺癌的诊断应用价值。方法选取2015年6月至2016年12月间苏州大学附属第二医院收治的103例前列腺外周带疾病患者的多参数磁共振成像(mp-MRI)表现。由两位医师对前列腺外周带病变进行PI-RADSv2评分,以病理检查结果作为金标准,分析两位医师诊断的一致性。通过绘制受试者工作特征(ROC)曲线及敏感度和特异度等指标,评估PI-RADSv2对外周带前列腺癌的诊断效能。结果两位医师评估外周带前列腺癌、临床显著癌和非癌病变Kappa值分别为0.75、0.84和0.66。PI-RADSv2诊断外周带前列腺癌的敏感度和特异度分别为80.2%和75.1%。PI-RADSv2诊断外周带前列腺临床显著癌的诊断敏感度和特异度分别为89.7%和84.6%。结论两位医师评估前列腺外周带病变的PIRADS评分有较高一致性,对前列腺外周带临床显著癌的评分一致性高,且PI-RADSv2对外周带前列腺临床显著癌有较高的敏感度和特异度,对前列腺外周带病变诊断具有一定的指导意义。 Objective To investigate the diagnostic value of Prostate Imaging Report and Data System (PI-RADSv2) in peripheral prostate cancer. Methods The multi-parametric magnetic resonance imaging (MRI) of 103 patients with peripheral prostatic disease was selected from the Second Affiliated Hospital of Soochow University between June 2015 and December 2016. PI-RADSv2 was scored by the two physicians for the lesions in the peripheral zone of the prostate. The results of the pathological examination were used as the gold standard to analyze the consistency of the diagnosis between the two doctors. The diagnostic efficacy of PI-RADSv2 on peripheral prostate cancer was assessed by plotting receiver operating characteristic (ROC) curves and sensitivity and specificity. Results Two physicians evaluated peripheral prostate cancer with Kappa values ​​of 0.75, 0.84 and 0.66 for clinically significant and non-cancerous lesions, respectively. The sensitivity and specificity of PI-RADSv2 in diagnosing peripheral prostate cancer were 80.2% and 75.1%, respectively. The diagnostic sensitivity and specificity of PI-RADSv2 in the diagnosis of clinically significant cancers in peripheral prostatic carcinoma were 89.7% and 84.6%, respectively. Conclusions The two physicians evaluated the PIRADS scores of peripheral zone lesions of the prostate with high consistency, high consistency of clinically significant cancers in the peripheral zone of the prostate, and high sensitivity and specificity of PI-RADSv2 in clinically significant cancers of the peripheral zone Degree of prostate peripheral lesions with a diagnosis of a certain significance.