传统疫苗的工作思路是,利用灭活版本的病毒来刺激人体产生抗体。然而,采用“天然”艾滋病病毒蛋白开发的疫苗却无法引发有效的免疫反应,这是由于艾滋病病毒能逃避免疫系统的检测,并快速变异为新的病毒株。上述两项研究认为,一种成功的艾滋病疫苗需要包括一系列相关但又略有区别的免疫原,经多轮免疫接种才能激发人体产生抗艾滋病病毒的广谱中和抗体。这与传统的“强化 The idea of ​​a traditional vaccine is to use the inactivated version of the virus to stimulate the body to produce antibodies. However, vaccines developed with ”natural“ HIV proteins fail to elicit an effective immune response because HIV can evade the detection of the immune system and rapidly mutate into new strains. According to the two studies, a successful AIDS vaccine needs to include a series of related but slightly different immunogens, and multiple rounds of immunization can stimulate the body to produce anti-HIV broad-spectrum neutralizing antibodies. This is enhanced with the traditional ”