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降纤酶是一种从蝮毒中分离出的含有纤溶酶的生物制剂,具有分解血浆纤维蛋白原、溶解血栓,降低血液粘度和血小板聚集作用,临床主要用于治疗缺血性心脑血管病,尤其对血栓前状态的治疗,有明显的优势。本文通过文献检索系统,收集了国内自1996~2009年来,各类医学期刊上发表的关于降纤酶不良反应的报道并加以分析和研究,旨在探讨发生药物不良反应的特点,以期为临床医师和患者安全合理地使用药物提供有效参考。
Defibrase is a fibrinolytic containing biological agent isolated from poisonous venom and has the functions of decomposing plasma fibrinogen, dissolving thrombus, lowering blood viscosity and platelet aggregation, and is mainly used for treating ischemic cardiovascular and cerebrovascular Disease, especially for the treatment of prethrombotic state, have obvious advantages. This article through the literature retrieval system, collected from 1996 to 2009, all kinds of medical journals published on defibrase adverse reactions reported and analyzed and studied to explore the characteristics of the occurrence of adverse drug reactions, with a view to clinicians And patients with safe and rational use of drugs provide a valid reference.