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目的观察米非司酮与利凡诺联合运用中孕引产的效果。方法108例口服米非司酮75mg1次/d2d。24h后经腹腔向羊膜腔里注入利凡诺80mg。结果观察组用药一次有效100%,对照组91.5%,其中疤痕子宫更明显。2组比较差异有显著性意义(P<0.01);其中宫缩启动时间、总产程、出血量、残留胎膜量均优于对照组。不良反应不明显。结论米非司酮利凡诺联合引产,使引产总产程缩短,减少胎盘膜残留,降低引产后出血及感染的发生。缩短住院时间,要求技术性不高,特别适用于基层医院农村病人。
Objective To observe the efficacy of mifepristone combined with rivanol in the induction of labor during pregnancy. Methods 108 cases of oral mifepristone 75mg1 times / d2d. 24h after the intraperitoneal injection of rivanol into the amniotic cavity 80mg. Results The observation group was 100% effective once, and 91.5% in the control group, in which the uterus of scar was more obvious. The difference between the two groups was significant (P <0.01). The contractile activation time, total labor, blood loss and residual fetal membranes were all better than the control group. Adverse reactions are not obvious. Conclusions Mifepristone Rivanol in combination with induction of labor can shorten the total labor induction and reduce placental membrane residue, reduce the incidence of post-labor bleeding and infection. Shorten the hospital stay, requiring less technical, especially for rural patients in grass-roots hospitals.