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目的探讨肺炎支原体感染诱发小儿哮喘的临床分析。方法对一汽总医院8 5例支气管哮喘患儿(观察组)和同期2 7例健康体检患儿(对照组)分别采血2 m l送检化验血清肺炎支原体(M P)抗体,进行统计学处理各数据间差异分别采用χ2和t检验,同时对临床资料进行系统性回顾。结果观察组血清M P抗体阳性率为4 5.9%而对照组血清M P抗体阳性率为2 2.2%,提示小儿哮喘患者存在肺炎支原体的感染。结论肺炎支原体感染是诱发支气管哮喘的重要病原体,肺炎支原体既是诱发支气管哮喘发作的感染源,又是过敏源,与哮喘发作有重要关系。当支气管哮喘发作应用常规治疗不能缓解或反复发作时,应注意肺炎支原体感染的可能,需要常规检查M P-I g M,及时加用大环内酯类抗生素如红霉素或阿奇霉素抗炎对于支气管哮喘缓解有明确疗效。
Objective To investigate the clinical analysis of Mycoplasma pneumoniae infection induced pediatric asthma. Methods Serum Mycoplasma pneumoniae (MP) antibodies were collected from 85 children with bronchial asthma (observation group) and 27 healthy children (control group) from the FAW General Hospital respectively for statistical analysis of the data The differences between the two groups were respectively analyzed by χ2 and t-test, and the clinical data were systematically reviewed. Results The positive rate of serum Mp antibody in observation group was 4 5.9%, while the positive rate of serum Mp antibody in control group was 2.2%, which suggested that Mycoplasma pneumoniae infection was found in pediatric asthma patients. Conclusion Mycoplasma pneumoniae infection is an important pathogen of bronchial asthma. Mycoplasma pneumoniae is not only the source of infection but also the source of allergy, which is associated with asthma attack. When the conventional treatment of bronchial asthma attack can not be relieved or recurrent episodes, should pay attention to the possibility of Mycoplasma pneumoniae infection, the need for routine examination M PI g M, plus macrolide antibiotics such as erythromycin or azithromycin in time for bronchial asthma Relieve a clear effect.