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本文用 APAAP 免疫组化方法对20例急性白血病进行免疫分型初步研究,结果表明17例(85%)急性白血病有特征性或相关性标志,其中非 T-ALL10例(Ⅰ、Ⅱ、Ⅲ型为3、2和5例),T-ALL 2、AML 1、AMMoL 及双表型各2例。不能确定表型1例(5%)及无标志者2例(10%),认为免疫组化有利于鉴别形态特殊的白血病。临床(瑞氏染色)诊断、细胞化学及免疫组化检测三项结果一致者9/16(56.25%),临床诊断与免疫组化两项一致者3例,临床诊断与细胞化学结果一致,而免疫表型不能确定及无标志者2例,三项结果均不一致者2例。10例住院患者的临床表现及预后与免疫表型无相关性。
In this paper, APAAP immunohistochemistry of 20 cases of acute leukemia immunophenotype preliminary study showed that 17 cases (85%) of acute leukemia has a characteristic or related markers, including non-T-ALL10 cases (Ⅰ, Ⅱ, Ⅲ 3, 2 and 5 cases), T-ALL 2, AML 1, AMMoL and two cases of each of the two cases. One case (5%) of the phenotype and 2 cases (10%) of the unmarked phenotypes were identified. Immunohistochemistry was considered as a useful method to identify the specific forms of leukemia. Clinical (Wright’s stain) diagnosis, cytochemistry and immunohistochemistry detection of three results were consistent 9/16 (56.25%), clinical diagnosis and immunohistochemistry in two cases were consistent, the clinical diagnosis and cytochemical results, and Immunophenotype can not be identified and no markers in 2 cases, three results were inconsistent in 2 cases. The clinical manifestations and prognosis of 10 inpatients had no correlation with the immunophenotype.