食管贲门粘膜撕裂综合征首先由Mallory和Weiss(1929)报道,故又称Mallory—Weiss综合征(简称MWS)。其临床特点为激烈干呕或呕吐之后发病,主要表现呕血和黑便。其发生率占上消化道出血病例的1～18%。1.病因与发病机理:食管、胃粘膜本身异常为发生MWS的基础。病人常伴有食管裂孔疝、食管、胃粘膜慢性炎症、消化性溃疡等。MWS常发生于 Esophageal and gastric mucosal tearing syndrome was first reported by Mallory and Weiss (1929), so it is also called Mallory-Weiss syndrome (MWS). The clinical features of severe retching or vomiting after onset, the main performance of hematemesis and melena. The incidence of upper gastrointestinal bleeding accounted for 1 to 18%. Etiology and pathogenesis: Esophageal and gastric mucosal abnormalities for the occurrence of MWS basis. Patients are often accompanied by esophageal hiatal hernia, esophagus, chronic inflammation of the gastric mucosa, peptic ulcer and so on. MWS often occurs in