论文部分内容阅读
将L-谷氨酰胺与苯磺酰氯缩合,合成了与抗瘤酮A_(10)(3-苯乙酰氨基-2,6-哌啶二酮)的水解产物相类似的标题化合物。采用X-射线单晶衍射分析法研究了它的晶体结构。标题化合物分子式C_(11)H_(14)N_2O_5S,Mr=286.30,晶胞参数:a=5.373(2)A,b=15.073(1)A,c=16.277(3)A;α=89.99(1)~0,β=90.00(2)~0,γ=89.96(2)~0;正交晶系,空间群P2_12_12_1,V=1318.3A~3,Z=4,D_c=1.442g/cm~3,最终晶体学偏差因子R=0.031。
By condensing L-glutamine with benzenesulfonyl chloride, the title compound was synthesized analogously to the hydrolysis product of the anti-tumor keton A 10 (3-phenylacetamido-2,6-piperidinedione). Its crystal structure was studied by X-ray single crystal diffraction analysis. The title compound, C 11 H 14 N 2 O 5 S, Mr = 286.30, unit cell parameters: a = 5.373 (2) A, b = 15.073 (1) A, c = 16.277 (3) A; ) 0, β = 90.00 (2) ~ 0, γ = 89.96 (2) ~ 0; orthorhombic, space group P2_12_12_1, V = 1318.3A ~ 3, Z = 4, D_c = 1.442g / cm ~ 3 , The final crystallographic deviation factor R = 0.031.