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目的总结瑞芬太尼联合异丙酚进行无痛人工流产术麻醉的效果。方法门诊随机选择终止妊娠的健康早孕妇女180例,平均分为3组,均静脉给药,A组给予地西泮复合盐酸哌替啶,B组单用丙泊酚,C组用小剂量瑞芬太尼复合丙泊酚。结果 A组患者术中有轻微疼痛;丙泊酚用药量C组较B组减少(P<0.05),减少幅度约40%;清醒时间(术后睁眼时间)B组、C组较A组明显缩短(P均<0.01),且C组较B组缩短明显(P<0.05)。3组患者均未出现恶心、呕吐和瘙痒等症状。A组发生注射静脉痛11例,体动反应9例;B组体动反应6例,呼吸暂停8例;C组发生呼吸暂停10例。结论瑞芬太尼复合丙泊酚无痛人流手术麻醉效果满意,丙泊酚用药量和并发症的发生明显减少。
Objective To summarize the effect of remifentanil combined with propofol on painless artificial abortion anesthesia. Methods A total of 180 healthy pregnant women randomly assigned to terminate pregnancy were enrolled in this study. The patients were equally divided into three groups, all of which were intravenously administered. Group A received diazepam combined with pethidine hydrochloride, group B received propofol alone, and group C received low- Fentanyl with Propofol. Results The patients in group A had mild pain during operation. The dosage of propofol in group C was decreased (P <0.05), and the reduction was about 40%. In awake time (open eye time) (P <0.01), and C group was shorter than that of B group (P <0.05). None of the 3 groups experienced nausea, vomiting and itching. A group of intravenous pain occurred in 11 cases, 9 cases of body motion response; B group body reaction in 6 cases, 8 cases of apnea; C group occurred apnea in 10 cases. Conclusion The anesthetic effect of remifentanil combined with propofol and painless ablation is satisfactory, and the dosage of propofol and the complication rate are significantly reduced.