论文部分内容阅读
为了探讨苍脂颗粒剂治疗脾胃病的胃粘膜保护作用，采用利血平模拟的大鼠脾虚证及亚急性阿斯匹林胃粘膜损伤模型，测定其对非蛋白质流基物质（NPSH）、谷胱甘肽过氧化物酶（GSH－px）、过氧化氢酶（CAT）、超氧化物歧化酶（SOD）及血浆过氧化脂质（LPO）等具有胃粘膜细胞保护作用物质的含量或活性的影响。结果显示，苍脂颗粒剂可以明显改善脾虚伴慢性胃粘膜病变大鼠及亚急性阿期匹林胃粘膜损伤大鼠的粘膜损伤程度，显著提高胃粘膜NPSH（F＜0．01）、GSH-px（P＜0．01）等细胞保护物质的水平．提示苍脂颗粒剂具有一定的胃粘膜细胞保护作用。
In order to investigate the protective effect of Cangzhi Granule on gastric mucosal protection of spleen-stomach disease, reserpine-simulated rat spleen deficiency syndrome and subacute aspirin gastric mucosal injury model were used to determine the non-protein-based substance (NPSH) and valley. GSH-px, catalase (CAT), superoxide dismutase (SOD), plasma lipid peroxidation (LPO), etc. Impact. The results showed that Cangzhi Granules can significantly improve the degree of mucosal damage in rats with spleen deficiency associated with chronic gastric mucosal lesions and subacute aciplinine gastric mucosal injury, and significantly increase gastric mucosal NPSH (F<0.01), GSH- The level of cytoprotective substances such as px (P<0.01). Cangzhi granules have a certain role in gastric mucosal cell protection.