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拟探讨MCE定量分析在缺血性心脏病上的诊断价值。对10例临床诊断冠心病的患者行MCE,从时间-强度曲线中获得造影剂再灌注强度峰值(SIpeak),再灌注时间(Rt),再灌注率(b)和心肌血流量(SI×b)。同一检查对象不同心肌节段的4个参数(SIpeak、Rt、b和SI×b)均有统计学上的差异(P<0.05),对照组和观察组SIpeak具有统计学上的差异,SIpeak预测缺血性心脏病的ROC曲线下面积(AUC)为0.782,最佳临界值为64.4,以SIpeak≤64.4来预测缺血性心脏病,敏感性83.3%,特异性69.0%。利用超声造影匹配成像技术能够较满意地显示心肌灌注状态,初步研究表明通过MCE及Qontrast多参数定量分析软件可以评价心肌梗死区和缺血区的血流灌注缺损。SIpeak是预测缺血性心脏病的敏感指标。
To investigate the quantitative value of MCE in the diagnosis of ischemic heart disease. MCE was performed on 10 patients with clinically diagnosed coronary heart disease, SIpeak, Rt, b and SI b were obtained from the time-intensity curve ). The four parameters (SIpeak, Rt, b and SI × b) of different myocardial segments of the same test group were statistically different (P <0.05), SIpeak of the control group and the observation group were statistically different, SIpeak prediction The area under the curve of ROC (AUC) of ischemic heart disease was 0.782, the best cut-off value was 64.4, the ischemic heart disease was predicted with SIpeak≤64.4, the sensitivity was 83.3% and the specificity was 69.0%. Myocardial perfusion can be demonstrated satisfactorily by contrast-enhanced ultrasound imaging. Preliminary studies have shown that perfusion defects in myocardial infarction and ischemic areas can be evaluated by MCE and Qontrast multi-parameter quantitative analysis software. SIpeak is a sensitive indicator of ischemic heart disease.