患者男,17岁,农民,因腹痛、少尿1周于1992年3月21日再次入院。2年前因进行性全身浮肿、血尿1个月首次入院。查体:严重浮肿、腹水(化验为漏出液),肝脾不大,肉眼血尿,尿蛋白12g/d,血浆白蛋白22.4g/l。诊断为肾病综合征Ⅱ型。开始服强的松50mg/d,8周后减为40mg/d。因疗效欠佳加用环磷酰胺0.2g隔日1次,静注至总量6g(70天)后 Male patient, 17 years old, farmer, due to abdominal pain, oliguria 1 week in March 21, 1992 re-admission. 2 years ago due to progressive systemic edema, hematuria, first hospitalization for 1 month. Physical examination: severe edema, ascites (fluid leak test), small spleen and liver, gross hematuria, urinary protein 12g / d, plasma albumin 22.4g / l. Diagnosis of nephrotic syndrome type Ⅱ. Starting service prednisone 50mg / d, reduced to 40mg / d after 8 weeks. Due to poor efficacy plus cyclophosphamide 0.2g every other day, intravenously until a total of 6g (70 days)