基于各项异性模型股骨肿瘤热疗三维温度分布模拟

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为了获得能够提供股骨肿瘤热疗时肿瘤及周围组织的三维温度分布规律的精确模型。本文运用mimics12.0医学图像处理软件,建立股骨三维模型,并根据灰度值与材料属性的关系,赋予股骨多种材料,使其几何形状和物理属性都和人体生理股骨接近。在设定骨组织热物性参数,给定边界和初始条件的情况下,利用有限元分析软件ansys11.0计算股骨肿瘤热疗时的三维温度分布规律。结果表明,多种材料赋值方式的各项异性股骨模型优于两种材料赋值方式的股骨模型,利用该模型进行三维温度场有限元分析,可以得出,股骨组织有较好的阻碍热传递的作用;在冠状面上,离热源越近,温度等值线越密集,温度梯度越大,且等温线成纵椭圆形;在矢状面上,等温线成类圆形,离热源越远,等温线越稀疏,温度梯度越小;在横断面上,等温线以热源为中心成椭圆分布,由内向外温度逐渐降低;股骨温度曲线在三维空间以热源为中心成椭球形分布,离热源越近,温度梯度越大。 In order to obtain an accurate model of the distribution of the three-dimensional temperature distribution of the tumor and the surrounding tissues during the hyperthermia of femur tumors. In this paper, mimics12.0 medical image processing software, the establishment of three-dimensional model of the femur, and according to the relationship between the gray value and the material properties, give the femur a variety of materials, the geometry and physical properties are close to the human physiology femur. In the setting of thermal physical parameters of bone tissue, given the boundary and initial conditions, the finite element analysis software ansys11.0 was used to calculate the three-dimensional temperature distribution pattern of femur tumor hyperthermia. The results show that the femoral model of the heterosexual femoral model with multiple material assignment is better than the femoral model with the two material assignment methods. By using the model, the three-dimensional finite element analysis of the temperature field shows that the femoral bone has better heat transfer resistance Effect; in the coronal plane, the closer to the heat source, the more dense the temperature contour, the greater the temperature gradient, and the isotherm into vertical oval; in the sagittal plane, the isothermal line into a circle, the farther away from the heat source, The more isothermal the isotherm, the smaller the temperature gradient; in the transverse section, the isotherm is distributed elliptically with the heat source as the center and the temperature gradually decreases from the inside to the outside; the femur temperature curve is ellipsoid distributed with the heat source in the three-dimensional space, Near, the greater the temperature gradient.
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