1　病例简介患者男 ,46岁。因缺血性脑血管病住院。入院后给维脑路通及川芎嗪静滴 ,10ｄ后停用上述药物改为 0 5 %ＧＮＳ 2 5 0ｍｌ,烟酸占替诺 6 0 0ｍｇ静滴 ,5 0滴 /ｍｉｎ ,用药 10ｍｉｎ后患者面部有针刺感 ,口唇肿胀 ,双眼睑浮肿 ,15ｍｉｎ后患者面色苍白、呼吸急促、胸 1 case description Patient male, 46 years old. Hospitalized for ischemic cerebrovascular disease. After admission to Venoruton and ligustrazine intravenous infusion, 10d after the withdrawal of the above drugs to 0 5% GNS 250ml, nicotinic acid contenuo 600 mg intravenous infusion, 50 drops / min, 10min after treatment of patients Facial acupuncture, swelling of the lips, double eyelid edema, 15min after patients pale, shortness of breath, chest