目的 本研究对急性脑梗死患者多形核白细胞(PMNLs)聚集及其与神经功能障碍程度和脑损伤间的关系进行临床动态观察。 方法 对88例临床诊断为急性脑梗死的患者(男62例,女26例,年龄45岁～75岁,平均58±6岁),用~(99m)Tc-HMPAO标记PMNLs;在SPECT下观察其聚集情况。经头颅CT扫描计算梗死体积,Mathew Scale法进行神经功能积分评定。于发病后3h～6h、6h～ Objective This study was conducted to investigate the clinical dynamic observation of the aggregation of polymorphonuclear leukocytes (PMNLs) and its relationship with the degree of neurological dysfunction and brain injury in patients with acute cerebral infarction. Methods Eighty-eight patients with acute cerebral infarction (62 males and 26 females, aged 45-75 years, mean 58 ± 6 years) were enrolled in this study. PMNLs were labeled with ~ (99m) Tc-HMPAO and observed by SPECT Its aggregation. The infarct volume was calculated by skull CT scan, and the neurological function score was evaluated by Mathew Scale method. After the onset of 3h ~ 6h, 6h ~