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目的:评价经导管部分脾栓塞术(PSE)对肝硬化并脾功能亢进患者肝功能的影响,并以此来评价PSE治疗对肝硬化患者肝功能改善意义和价值。方法:24例确诊为肝炎后肝硬化并脾功能亢进患者经PSE治疗观察肝功能治疗变化及通过Child Pugh的评分评价基础肝功能状态及术后1、3、6个月肝功能的状态。结果:术前Child Pugh的评分为7.20±1.10,治疗后1、3、6个月评分均降低,分别为6.98±1.12、6.40±1.13、5.93±1.13。于术前比较差异均有统计学意义(P<0.05)。结论:对于肝硬化并脾功能亢进患者,PSE治疗后对肝功能有一定程度改善。
Objective: To evaluate the effect of transcatheter partial splenic embolization (PSE) on liver function in patients with cirrhosis and hypersplenism, and to evaluate the significance and value of PSE treatment in improving liver function in patients with liver cirrhosis. Methods: Twenty-four patients with post-hepatitis cirrhosis and hypersplenism were observed by PSE to observe the change of liver function and the state of liver function and the status of liver function at 1, 3 and 6 months after operation by Child Pugh score. Results: The preoperative Child Pugh score was 7.20 ± 1.10, and the scores at 1, 3, and 6 months after treatment were all decreased, which were 6.98 ± 1.12, 6.40 ± 1.13 and 5.93 ± 1.13 respectively. The differences were statistically significant before operation (P <0.05). Conclusions: For patients with cirrhosis and hypersplenism, PSE has a certain degree of improvement in liver function.