目的分析医院消毒与灭菌的效果,预防医院感染。方法对医院空气、物体表面、医务人员手、使用中消毒剂、透析用水和内镜等进行采样监测,并对监测结果进行分析。结果共采样3 613份,平均总合格率97.1%,其中使用中消毒液、医务人员手、内镜、物体表面、空气和透析用水合格率分别为100.0%、99.2%、97.3%、97.6%、93.9%和92.5%,均未检出致病菌;2005-2011年合格率分别为95.8%、98.7%、97.1%、97.3%、95.2%、98.7%和97.8%。结论 2005-2011年7年间该医院消毒与灭菌效果良好。 Objective To analyze the effect of hospital disinfection and sterilization to prevent nosocomial infection. Methods The hospital air, the surface of the object, the hand of the medical staff, the use of disinfectants, dialysis water and endoscopy were sampled and monitored, and the monitoring results were analyzed. Results A total of 3 613 samples were collected, with an average total passing rate of 97.1%. The pass rates of disinfectant, medical staff, endoscope, surface of objects, air and dialysis water were 100.0%, 99.2%, 97.3% and 97.6% 93.9% and 92.5% respectively. None of the pathogens were detected. The passing rates in 2005-2011 were 95.8%, 98.7%, 97.1%, 97.3%, 95.2%, 98.7% and 97.8% respectively. Conclusion The hospital disinfection and sterilization in 7 years from 2005 to 2011 was effective.