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目的探讨莫沙比利对胶囊内镜检查中胃肠通过时间的影响。方法将本院2008年10月至2010年12月间做胶囊内镜患者40例纳入本研究,随机分为2组,每组20例。试验组胶囊内镜检查前口服莫沙比利5mg,对照组则不服药物,记录胶囊内镜检查中的胃排空时间、小肠通过时间,并统计小肠检查完成率。结果试验组平均胃排空时间明显短于对照组(36minvs.54min,P<0.05),2组小肠通过时间(221minvs.248min)差异无统计学意义(P>0.05),试验组小肠检查完成率较对照组高(95%,65%,P=0.044)。结论检查前口服莫沙比利能缩短胶囊内镜的胃排空时间,并提高小肠检查完成率。
Objective To investigate the influence of mosapride on the transit time of gastrointestinal in capsule endoscopy. Methods Forty patients who underwent capsule endoscopy in our hospital from October 2008 to December 2010 were enrolled in this study and randomly divided into two groups of 20 patients. Test group capsule endoscopy before oral mosapride 5mg, the control group was not satisfied with the drug, record the time of gastric emptying capsule endoscopy, small intestine through time, and statistics of the completion rate of small intestine examination. Results The average gastric emptying time in the experimental group was significantly shorter than that in the control group (36min vs. 54min, P <0.05), and there was no significant difference in the passage of small intestine between the two groups (221min vs. 248min) (P> 0.05) Higher than the control group (95%, 65%, P = 0.044). Conclusions The oral administration of mosapride before shortening can shorten the time of gastric emptying in capsule endoscopy and improve the rate of completion of small bowel examination.