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目的研究宫腔镜治疗慢性宫颈炎患者对超敏C反应蛋白(hs-CRP)、肿瘤坏死因子(TNF)、白细胞介素(IL)水平的改善作用。方法 167例慢性宫颈炎患者,根据自愿原则分为实验组(87例)和对照组(80例)。实验组采取宫腔镜下电波刀治疗,对照组采取激光手术治疗,经治疗1个月后,观察患者的临床体征情况,以hs-CRP、TNF和IL水平进行有效对比,观察其恢复程度。结果治疗后,实验组患者血清中各炎性因子恢复情况与对照组比较,差异具有统计学意义(P<0.05)。实验组治疗总有效率为97.70%,明显高于对照组的87.50%,差异具有统计学意义(P<0.05)。实验组疾病复发率为14.94%(13/87),明显低于对照组的27.50%(22/80)(P<0.05)。结论通过宫腔镜下电波刀治疗慢性宫颈炎,相比传统激光手术治疗办法,能更有效的降低术后不良症状,可在临床手术治疗中进行推广使用。
Objective To study the effects of hysteroscopy on the improvement of hs-CRP, TNF and IL levels in patients with chronic cervicitis. Methods 167 patients with chronic cervicitis were divided into experimental group (87 cases) and control group (80 cases) according to the voluntary principle. The experimental group was treated with hysteroscopic wave knife, the control group was treated with laser surgery. After 1 month of treatment, the clinical signs of the patients were observed. The levels of hs-CRP, TNF and IL were compared and the recovery was observed. Results After treatment, the recovery of inflammatory cytokines in the experimental group was significantly different from that in the control group (P <0.05). The total effective rate of the experimental group was 97.70%, which was significantly higher than 87.50% of the control group, the difference was statistically significant (P <0.05). The recurrence rate of the experimental group was 14.94% (13/87), which was significantly lower than that of the control group (27.50%, 22/80) (P <0.05). Conclusion The treatment of chronic cervicitis by hysteroscopic electric wave knife can reduce the postoperative adverse symptoms more effectively than traditional laser surgery and can be widely used in clinical operation.