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目的:分评氟喹诺酮类药物的不良反应评价。方法回顾性分析76例使用氟喹诺酮类药物出现不良反应患者的临床资料。结果:男性患者出现不良反应的几率57(75%)高于女性患者,差异有统计学意义(P<0.05)。出现不良反应的系统主要集中在神经系统、消化系统、循环系统、免疫系统、血液系统、泌尿系统,神经系统出现不良反应的人数最多,24(31.5%)。结论:在应用氟喹诺酮类药物前要考虑患者是否患者有影响药物作用的合并症,降低出现不良反应的几率;患者使用氟喹诺酮类药物治疗后要养成良好的生活习惯,也可以降低出现不良反应的几率。
Objective: To evaluate the adverse reactions of fluoroquinolones. Methods The clinical data of 76 patients with adverse reactions of fluoroquinolones were retrospectively analyzed. Results: The incidence of adverse reactions in male patients was 57 (75%) higher than that in female patients, the difference was statistically significant (P <0.05). The system with adverse reactions mainly concentrated in the nervous system, digestive system, circulatory system, immune system, hematological system, urinary system and nervous system with the largest number of adverse reactions (24%, 31.5%). CONCLUSIONS: Patients should be considered for any comorbidities that affect drug effects before use of fluoroquinolones to reduce the risk of adverse reactions. Patients who develop fluoroquinolones should develop good habits and may also reduce adverse effects Chance of reaction