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降压药联合应用的目的,是为了使药物发挥最大的降压效果,并使副作用减至最低限度。由于个体差异很大,联用的降压药不能做硬性规定。多数降压药联用时,其作用主要是相加的。选择降压药时,可先选用口服利尿药,及病人易于耐受的药物。利血平、甲基多巴、呱乙啶、可乐宁,都有致使钠潴留的作用,所以可与口服利尿药合用,并相应的减少上述药物的使用量。肼苯达嗪有拮抗心得安及呱乙啶使心动减缓,及心肌收缩反应的作用,所以与后二药联合使用可使副作用减低。优降宁具有一定的兴奋作用,可以抵消利血平所致的部分抑鬰、倦怠等副反应,可以二者合用,每日上午或清晨服用优降宁,临睡时服用利血平,每日各服一次。并可用单量间断服用的口服利尿药
The purpose of the combination of antihypertensive drugs is to maximize the antihypertensive effect of the drug and to minimize the side effects. Due to the large individual differences, the combination of antihypertensive drugs can not do the hard rules. When combined with most antihypertensive drugs, its effect is mainly additive. Select antihypertensive drugs, the first choice of oral diuretics, and the patient is easily tolerated drugs. Reserpine, methyldopa, Gueni pyridine, clonidine, have caused the role of sodium retention, it can be combined with oral diuretics, and the corresponding reduction in the use of these drugs. Hydralazine has antagonism and guanethidine bradycardia bradycardia and myocardial contractile response, so with the latter two drugs can reduce the side effects. You-Nyoning has a certain excitement effect, you can offset reserpine-induced partial depression, fatigue and other side effects, you can combine the two daily morning or morning taking gloria, reserpine when taking reserpine, each Daily service time. And available single intermittent taking oral diuretics