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动物病毒载体在基因转移和治疗中有着重要意义。逆转录病毒载体是目前用子基因治疗最为成功的,已用于多种病例的临床研究;腺病毒载体成功地对多种基因进行了转移,并用于囊性纤维病的基因治疗临床研究;腺病毒相关病毒载体和单纯疤疾病毒载体介导的基因转移在体外培养细胞和动物实验中都取得成功,在某些疾病的基因治疗中显示出特殊的应用价值。
Animal virus vectors are of great importance in gene transfer and therapy. The retroviral vector is currently the most successful treatment with the gene therapy, has been used in clinical studies in a variety of cases; adenovirus vector successfully transferred a variety of genes, and for the clinical study of gene therapy for cystic fibrosis; gland Virus-associated virus vectors and simple scar virus vector-mediated gene transfer in vitro and animal experiments have been successful in the gene therapy of certain diseases has shown a special value.