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目的明确2012年菏泽市手足口病(HFMD)实验室检测病原学及分布特点。方法采集临床诊断为手足口病病例粪便或咽拭子标本,Real-Time PCR对肠道病毒EV71型、CA16型进行检测,并对检测结果进行分析。结果 396份临床标本中核酸检测阳性380份,检出率95.96%。阳性病例分布在各个县区,但EV71、CA16分布各有差异;不同月份发病率不同,3-5月仍为高发期;1~3岁仍是HFMD的高发年龄段,EV71依然是引发重症病例的主要病原。结论 2012年菏泽市HFMD病原以EV71为主,发病分布在不同区域、年龄、月份有差异。
Objective To determine the etiology and distribution of HFMD laboratory in Heze City in 2012. Methods The specimens of stool or throat swab in clinical diagnosis of HFMD were collected. Real-Time PCR was used to detect enterovirus EV71 and CA16, and the detection results were analyzed. Results Among the 396 clinical samples, 380 were positive for nucleic acid test, the detection rate was 95.96%. Positive cases were found in all counties, but the distributions of EV71 and CA16 were different. The morbidity in different months was still high in March to May. The incidence of HFMD in 1 ~ 3 years old was still high, and EV71 was still the cause of severe cases The main pathogen. Conclusion The prevalence of HFMD in Heze City in 2012 was mainly EV71. The incidence of HFMD in different regions, ages and months was different.