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关于恶性肿瘤患者体内乳酸脱氧酶(LDH)的变化.国内外学者已有较多论述。但其对于急性白血病预后估计,文献报道尚少。本文总结了44例急性白血病患者血清LDH测定结果,并探讨其在估计急性白血病的预后中的价值。对象及方法半年内住院治疗的各型白血病患者共46例,其中2例因合并乙型病毒性肝炎未列入统计数,余44例均列入观察总数。患者均经本所细胞形态、组织化学检查后确诊,部分急性淋巴细胞性患者还做了细胞免疫学分型检查。其中急淋13例,急非淋29例,慢粒急淋变2例。年龄18～63岁,平均37岁。男26例,女18例。统计分五组:初治组16例,均为新确诊入院的患者,在化疗前取血测定;死亡组11例次,取死亡前的测定值(其中包括初治组的4例死亡患者死亡
About the changes of lactate dehydrogenase (LDH) in patients with malignant tumors, scholars at home and abroad have more discussion. However, its prognosis for acute leukemia has been reported in the literature. This article summarizes the results of serum LDH in 44 patients with acute leukemia and explores its value in estimating the prognosis of acute leukemia. Subjects and Methods Sixty-six patients with various types of leukemia were hospitalized within six months. Two of them were excluded from the statistics due to the merger of hepatitis B virus. The remaining 44 cases were included in the total number of observation. Patients were confirmed by the cell morphology, histochemical examination, some patients with acute lymphoblastic cell immunology also did a typing test. Of which acute leaching in 13 cases, acute non-leaching in 29 cases, acute leukocytosis in 2 cases. Age 18 ~ 63 years old, average 37 years old. 26 males and 18 females. Statistics were divided into five groups: untreated group of 16 patients, all newly diagnosed patients admitted to chemotherapy before blood determination; death group 11 cases, take the measured value before death (including the newly diagnosed group of 4 deaths