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本文报告采用胼胝体前部切开加双侧扣带回前都毁损术治疗全身性强直-阵挛性发作并有精神性发作或精神障碍型顽固性癫痫4例的初步经验。临床资料女性2例,男性2例。病程为5～18年。表现为发作性意识丧失,全身性强直-阵挛性抽搐。在大发作间期有发作性精神异常或精神障碍,易怒,易激动,骂人,攻击他人,毁物,甚至自伤,奔跑不归家等。智商1例>70分,3例<70分。EEG均异常。以θ波和δ波为主。脑CT扫描:1例正常.3例分别为:脑发育不全、脑萎缩或局部萎缩。患者长期服抗癫痫药物,多种治疗方法无效。3例不能正常生活和学习。神经系统检查:3有神经系统残疾症状.其中有失明、耳聋、轻偏瘫、语言障碍等。4例经过神经内外科、精神科治疗.诊断为癫痫大发作(全身性强直一阵挛性)合并有精神性发作或精神障碍(情感型)。手术在显微镜下显示胼胝体前
This paper reports the initial experience of using corpus callosum anterior incision plus bilateral cingulate gyrus for the treatment of 4 cases of generalized tonic-clonic seizures with or without mental disability or mental retardation epilepsy. Clinical data of 2 females, 2 males. Course of 5 to 18 years. Showed as episodic loss of consciousness, generalized tetanus - clonic convulsions. In episodes of episodes of episodes of mental disorders or mental disorders, irritability, irritability, curse, attack others, destroy the material, and even self-injury, running away from home and so on. 1 case of IQ> 70 points, 3 cases <70 points. EEG are abnormal. To θ wave and δ wave dominated. Brain CT scan: 1 case of normal .3 cases were: brain hypoplasia, brain atrophy or local atrophy. Patients with long-term antiepileptic drugs, a variety of treatment ineffective. 3 cases can not live and study normally. Nervous system examination: 3 There are symptoms of nervous system disability, including blindness, deafness, hemiparesis, language problems. Four cases were neurosurgery and psychiatric treatment, diagnosed as epileptic seizures (generalized tonic-clonic) with psychotic or mental disorders (affective). Surgery under the microscope shows the corpus callosum