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53例早产儿在NICU 住院过程中发生呼吸暂停,发病诱因以缺氧、酸中毒最多,其次为低体温和低血糖,原发性仅3例。用氨茶硷治疗30例,其中17例有效,13例无效.有效病例氨茶硷首次剂量均在5mg/kg 以上,并且无严重肺脑疾病。32例用呼吸器作辅助通气治疗,其中12例因氨茶硷无效改用呼吸器,另外20例均有严重原发病。53例经治疗后死亡6例,自动出院3例,存活44例,存活率为83.0%。文中对早产儿呼吸暂停的病因、氨茶硷疗效以及辅助通气治疗略加讨论。
Fifty-three premature infants underwent apnea during NICU hospitalization. The predisposing factors were hypoxia, acidosis, followed by hypothermia and hypoglycemia, with only three cases of primary hypoxia. Thirty cases were treated with aminophylline, of which 17 cases were effective and 13 cases were ineffective.Affective cases The first dose of aminophylline was above 5mg / kg, and no serious pulmonary brain disease. Thirty-two cases were treated with ventilator assisted ventilation, of which 12 cases were ineffective with aminophylline, and the other 20 cases had severe primary disease. Of the 53 patients, 6 died after treatment, 3 were discharged automatically, and 44 survived, with a survival rate of 83.0%. The etiology of apnea in preterm infants, aminophylline efficacy and adjuvant ventilation slightly discussed.