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目的:观察平肝降压汤联合西医常规疗法治疗高血压合并高血脂患者的临床效果。方法:选取于本院就诊的150例高血压合并高血脂患者,随机分为对照组和观察组各75例。对照组给予氢氯噻嗪片联合辛伐他汀片治疗,观察组则在对照组治疗基础上给予平肝降压汤内服治疗,15天为1疗程,连续治疗6疗程。观察2组血压、血脂水平的改善情况,随访6月观察患者心脑血管疾病的发生情况。结果:治疗前,2组血压、血脂各指标比较,差异均无统计学意义(P>0.05)。治疗后,2组收缩压、舒张压均较治疗前有所降低(P<0.05),且趋于稳定,观察组血压的下降幅度较对照组突出(P<0.05)。2组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平均较治疗前有所降低(P<0.05),高密度脂蛋白胆固醇(HDL-C)水平均较治疗前有所升高(P<0.05),观察组改善的程度较对照组明显(P<0.05)。治疗后随访6月,对照组心脑血管疾病发生率为22.7%,明显高于观察组(9.3%),差异有统计学意义(P<0.05)。结论:平肝降压汤联合西医常规疗法降压、降脂疗效确切,远期心脑血管疾病发生率低,是治疗高血压合并高血脂疾病的有效方案。
Objective: To observe the clinical efficacy of “Pinggan Jianpi Decoction” combined with western routine therapy in the treatment of patients with hypertension and hyperlipidemia. Methods: A total of 150 hypertensive patients with hyperlipidemia treated in our hospital were randomly divided into control group and observation group of 75 cases each. Hydrochlorothiazide tablets and simvastatin tablets were given to the control group. The observation group was treated with Pinggan antihypertensive decoction on the basis of the control group. One course of treatment was 15 days and the course of treatment was 6 courses. Blood pressure and blood lipid levels were observed in two groups. The incidence of cardiovascular and cerebrovascular diseases was observed in 6 months follow-up. Results: Before treatment, there was no significant difference between the two groups in blood pressure and blood lipid (P> 0.05). After treatment, systolic blood pressure and diastolic blood pressure in both groups were lower than those before treatment (P <0.05), and tended to be stable. The decrease of blood pressure in the observation group was more prominent than that in the control group (P <0.05). The levels of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in the two groups were lower than those before treatment (P <0.05), and the levels of high-density lipoprotein cholesterol (P <0.05). The degree of improvement in the observation group was significantly higher than that in the control group (P <0.05). After treatment, the incidence of cardiovascular and cerebrovascular diseases in control group was 22.7% at 6 months after treatment, which was significantly higher than that in observation group (9.3%), the difference was statistically significant (P <0.05). Conclusion: Pinggan antihypertensive Decoction combined with Western conventional therapy blood pressure, lipid-lowering effect is exact, long-term cardiovascular and cerebrovascular disease is low, is an effective treatment for hypertension complicated with hyperlipidemia.