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晚发性维生素K 缺乏致婴儿颅内出血(以下称本病),临床少见,易误诊,病死率较高,现将我科遇治5例报道如下。临床资料:男4例,女1例,年龄最小40天,最大90天。均是足月顺产,母乳喂养,无Vitk 注射史,家族中均无出血疾病史。发病前曾分别用氨苄青霉素,新青Ⅱ,新霉素,痢特灵。5例均突然发病,烦燥、惊厥、意识障碍,贫血。其中呕吐3例,发热2例,采血部位出血不止2例,皮肤出血点1例,肌注部血肿1例;囟门均饱满,脑膜刺激征均阳性,实验室:Hb<8g 3
Late onset of vitamin K deficiency caused by intracranial hemorrhage in infants (hereinafter referred to as the disease), clinical rare, easily misdiagnosed, high mortality rate, now we encounter 5 cases were treated as follows. Clinical data: 4 males and 1 females, the youngest 40 days, the maximum 90 days. All were full-term spontaneous, breastfeeding, no Vitk injection history, no history of bleeding in the family history. Before the onset of ampicillin, respectively, new blue Ⅱ, neomycin, furazolidone. 5 cases were sudden onset, irritability, convulsions, disturbance of consciousness, anemia. Among them, vomiting in 3 cases, fever in 2 cases, blood bleeding site more than 2 cases, skin bleeding in 1 case, intramuscular injection hematoma in 1 case; fontanelle were full, meningeal irritation were positive, laboratory: Hb <8g3