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为了解郑州地区幽门螺杆菌（ＨＰ）感染流行情况，研究ＨＰ与常见消化道疾病的关系。采用ＥＬＩＳＡ法对５５１人进行了血清ＨＰ抗体检测。结果表明：人群ＨＰ感染率为４２．８３％。１０岁以下儿童ＨＰ感染率为３２．１４％，有消化不良症状者ＨＰ感染率为６７．５４％，其中有明确的消化性溃疡、慢性胃炎者ＨＰ感染率分别为８１．３９％、８２．０５％，无症状人群ＨＰ感染率为３３．５％，差异有显著性（Ｐ＜０．０１）。ＨＰ感染者的家庭成员感染率为７２．２２％，显著高于一般人群（Ｐ＜０．０５）。
To understand the prevalence of Helicobacter pylori (HP) infection in Zhengzhou, the relationship between HP and common gastrointestinal diseases was studied. 551 people were tested for serum HP antibody by ELISA. The results showed that the HP infection rate was 42.83%. The HP infection rate of children under 10 years old was 32.14%, HP infection rate was 67.54% with dyspeptic symptoms, including clear peptic ulcer, chronic gastritis HP infection rates were 81.39%, 82 respectively. 05%, HP infection rate in asymptomatic population was 33.5%, the difference was significant (P <0.01). The infection rate of family members of HP infected persons was 72.22%, significantly higher than that of the general population (P <0.05).