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随着医学细胞遗传学的进展,人们日益认识到,染色体畸变在医学及生物学上的意义和重要性。体细胞染色体畸变,主要危及畸变者自身。而生殖细胞的染色体畸变,将危及子代。因此,其潜在的影响比前者更加重要。已知某些化学试剂和药物,能引起染色体的断裂和重排。作为口服避孕药的固醇类药物,将对体细胞或生殖细胞产生何种影响?自然成为大家所关注的问题。尤其在长期口服避孕药后再妊娠时,胚胎的发育是否会受激素变化的干扰?这些问题是值得深入探讨的。迄今,已在人体和实验动物方面,
With the progress of medical cytogenetics, people are increasingly aware of the medical significance and importance of chromosomal aberrations. Chromosome aberration of somatic cells, the main endanger the aberrant themselves. Chromosomal aberrations in germ cells, however, threaten offspring. Therefore, its potential impact is more important than the former. Known to some of the chemical reagents and drugs, can cause chromosome rupture and rearrangement. Steroid drugs as oral contraceptives, what will happen to somatic cells or germ cells? Naturally become everyone’s concern. Especially in the long-term oral contraceptives after pregnancy, the development of embryos will be affected by hormone changes? These issues are worthy of further study. So far, in human and laboratory animals,