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应用DNA解旋荧光测定法(FADU)检测DNA链断裂,研究不同浓度脑灵素对受到60Co-γ线照射后肿瘤细胞及淋巴细胞DNA链断裂的效应。结果表明,脑灵素对受照后的人红白血病细胞(K562)有促进DNA链断裂的作用;而对受照后人血淋巴细胞不表现此作用。
DNA strand breaks were detected by DNA dextropic fluorimetry (FADU), and the effect of different concentrations of brain-stem cells on DNA strand breaks in tumor cells and lymphocytes irradiated by 60 Co-γ ray was studied. The results showed that, Nao Ling Su on the irradiated human erythroleukemia cells (K562) to promote DNA strand breaks role; and irradiated human blood lymphocytes do not show this effect.