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目的:探究宫颈人乳头状瘤病毒(HPV)感染类型及其对宫颈癌前筛查的意义。方法:选取有性生活史的妇女1000名作为研究对象,均为本院妇科门诊及住院自2014年6月至2015年6月所接收,主要通过HPV检测及薄层液基细胞检测法筛查,检测妇女宫颈外口及宫颈管脱落细胞,并联合运用PCR结合反向斑点杂交法对HPV进行分型,对比分析最终的检测结果。结果:检查者中,检测出HPV感染者321例,其中21种HPV亚型共检出17种,低危亚型占2种,高危亚型占15种。结论:该地区主要以HPV16、52、11、58、31、33亚型为HPV感染亚型,同时感染类型中与宫颈癌有关的是:HPV16、52、58、33亚型。
Objective: To explore the types of cervical papilloma virus (HPV) infection and its significance in cervical precancerous screening. Methods: A total of 1000 women with a history of sexual life were selected as subjects. All of them were received by our gynecology clinic and hospitalized from June 2014 to June 2015. They were mainly screened by HPV test and thin-layer liquid-based cell test , Detecting the cervix uterus and exfoliated cells of the cervix, and using PCR combined with reverse dot blot hybridization to HPV typing, comparative analysis of the final test results. RESULTS: Of the examiners, 321 HPV infections were detected, of which 17 were detected in 21 HPV subtypes, 2 in low-risk subtypes and 15 in high-risk subtypes. Conclusion: HPV16,52,11,58,31,33 subtypes are mainly HPV subtypes in this area, and HPV16,52,58,33 subtypes are associated with infection types.