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[目的]探讨内镜窄波成像(NBI)下Barrett食管(BE)上皮形态变化特点与病理组织学诊断结果的符合率。[方法]选取胃镜检查疑诊为BE的102例患者,NBI模式下实时观测BE上皮形态变化特点,判断肠上皮化生类型,随后对所检查部位黏膜靶向活组织病理检查,分析两者诊断结果的相符率。[结果]91例患者被确诊为BE,NBI模式下根据小凹的形态特点分成规则无增粗型、规则增粗型、紊乱增粗型,与之相对应的为胃底腺型、贲门腺型、特殊肠上皮化生型,经靶向活组织病理检查后证实其准确度分别为85.7%、86.6%、88.4%。[结论]NBI可准确分辨BE上皮形态变化的组织类型,靶向活检提高组织病理学准确性,两者诊断符合率达≥85%。
[Objective] To investigate the coincidence rate of the morphological changes of Barrett’s esophagus (BE) epithelium and histopathological diagnosis under narrow-wave imaging (NBI). [Methods] 102 patients with suspected BE as gastroscopy were selected. Under the NBI mode, the characteristics of BE epithelial morphological changes were observed in real time. The type of intestinal metaplasia was judged. Subsequent mucosal biopsy of the examined site was performed to analyze the diagnosis of both. The consistency of the results. [Results] Ninety-one patients were diagnosed as BE. According to the morphological characteristics of the fovea, the NBI model was divided into no thickening type, regular thickening type, and disorder thickening type. The corresponding type was gastric fundal gland type, cardia adenocarcinoma. Types and special intestinal metaplasia were confirmed by targeted biopsy to be 85.7%, 86.6%, and 88.4%, respectively. [Conclusion] NBI can accurately distinguish the tissue types of BE epithelial morphological changes, target biopsy to improve histopathological accuracy, and the diagnostic coincidence rate of the two is ≥ 85%.