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目的:观察肠胃康颗粒与健胃消食口服液治疗小儿厌食症的临床疗效差异。方法:采用随机数字表法将浙江省衢州市妇幼保健院儿科门诊2012年1月至2013年12月收治的94例厌食症小儿分为肠胃康颗粒组和健胃消食口服液组各47例,肠胃康颗粒组采用肠胃康颗粒治疗,健胃消食口服液组采用健胃消食口服液治疗,比较两组患儿治疗4周后的临床疗效差异。结果:治疗前肠胃康颗粒组患儿的食欲、食量、面色、自汗盗汗、性情、大便情况、舌象及总积分与健胃消食口服液组比较差异无统计学意义(P>0.05),治疗后两组患儿各项中医证候积分较治疗前均显著下降,肠胃康颗粒组较健胃消食口服液组下降更加显著(P<0.05)。治疗前两组患儿的食量、体质量差异无统计学意义(P>0.05),治疗后肠胃康颗粒组患儿的食量显著高于健胃消食口服液组(P<0.05),两组患儿的食量均较治疗前显著增加(P<0.05)。治疗前两组患者皮下脂肪厚度、APK、血红蛋白、唾液锌含量差异无统计学意义(P<0.05),治疗后肠胃康颗粒组患儿皮肤下脂肪厚度、AKP、血红蛋白、唾液锌含量均显著高于健胃消食口服液组(P<0.05)。肠胃康颗粒组总有效率显著高于健胃消食口服液组(P<0.05)。结论:肠胃康颗粒治疗小儿厌食症的临床疗效优于健胃消食口服液。
Objective: To observe the difference of clinical curative effect between treating the anorexia of children by using the capsule of stomach and stomach and invigorating the stomach and stomach. Methods: A total of 94 children with anorexia admitted to Zhejiang Quzhou Maternal and Child Health Care Hospital from January 2012 to December 2013 were randomly divided into two groups: Changweikang granule group was treated with Changweikang granule, while Jianweixiaoshi oral liquid group was treated with Jianweixiaoshi oral liquid, and the difference of clinical curative effect was compared between the two groups after 4 weeks of treatment. Results: There was no significant difference in appetite, appetite, appetite, complexion, spontaneous perspiration, temperament, stool, tongue and total score between the two groups before and after treatment with Jianweixiaoshi oral liquid group (P> 0.05) After treatment, the scores of TCM syndromes in both groups were significantly decreased compared with those before treatment, and there was a significant difference between the two groups (P <0.05). There was no significant difference in food intake and body weight between the two groups before treatment (P> 0.05). After treatment, the appetite of children in Weike Kang granules group was significantly higher than that of Jianweixiaoshi oral liquid group (P <0.05) Children’s food intake than before treatment was significantly increased (P <0.05). There was no significant difference in subcutaneous fat thickness, APK, hemoglobin and salivary zinc content between the two groups before treatment (P <0.05). After treatment, the subcutaneous fat thickness, AKP, hemoglobin and salivary zinc content were significantly higher Yujianweixia oral solution group (P <0.05). The total effective rate of GGT group was significantly higher than that of Jianweixiaoshi oral liquid group (P <0.05). Conclusion: The clinical effect of “Weiweikang Granule” in treating children with anorexia is better than that of “Jianwei Xiaoshi” oral liquid.