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本试验观察三种长效、缓释降压药对75例原发性高血压病人的疗效,及对血脂代谢的影响。发现三组药均有明显的降压效果;第三代β阻滞剂Bisoprolol有明显的降低心率的作用。ACEI类第三代降压药perindopril及钙拮抗剂第三代产品Isoptin,SR可不同程度的使血浆胆固醇及甘油三酯、低密度脂蛋白降低,高密度脂蛋白升高;而Bisoprolol不具备降低血浆胆固醇及甘油三脂的作用。
This experiment observed three kinds of long-acting, sustained release antihypertensive drugs on 75 patients with essential hypertension efficacy, and lipid metabolism. Three groups of drugs were found to have significant antihypertensive effect; the third generation of β blockers Bisoprolol significantly reduce the role of heart rate. ACEI third-generation antihypertensive drugs perindopril and calcium antagonist third-generation products Isoptin, SR to varying degrees of plasma cholesterol and triglycerides, low-density lipoprotein decreased, high-density lipoprotein increased; and Bisoprolol do not have to reduce Role of plasma cholesterol and triglycerides.