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最近,日本厚生省发表了1982年度医药品副作用监测报告。截至1983年3月的一年间内,全国各监护医院共报告了822件副作用事例,其中死亡20例。医药品副作用监护制度是指定全国1,001所大学医院及综合医院为监护医院,收集和评价新的副作用、严重副作用情报,并探索相应对策。虽然未必能确定副作用与医药品的因果关系,但1982年度有822件副作用事例发生。其中医药品所致者815件,医疗用品所致者7件。报告列举了引起副作用最多的药品,如羟氨苄青霉素、先锋霉素Ⅳ等抗菌素制剂、扑湿痛、吡氧噻嗪等解热镇痛消炎剂、吉草酸倍他米松等外用药,以上都是应用频度较高的药物。
Recently, Japan’s Ministry of Health published a 1982 report on side effects of pharmaceuticals. As of March 1983, a total of 822 cases of side effects were reported to various hospitals in China, including 20 deaths. The monitoring system for the side effects of pharmaceuticals is to designate 1,001 university hospitals and general hospitals as care hospitals in the country to collect and evaluate new side effects and serious side effects and to explore appropriate countermeasures. Although it may not be possible to determine the causal link between side effects and medicines, 822 cases of side effects occurred in 1982. Among them, 815 were caused by medicines and 7 due to medical supplies. The report lists the drugs that cause the most side effects, such as amoxicillin, cephalosporin IV and other antibiotics, psoriasis, piroxicam and other antipyretic analgesic and antipyretic agents, betamethasone oxalate and other external drugs, all of which are High frequency of use of drugs.