随着社会的老龄化,缺血性中风已成为一种世界范围内的主要致残、致死因素。中风发生后的神经细胞死亡是渐进长时程的过程,对于其机理的研究有助于有效的中风治疗,不仅可以缓解个人的病痛,而且还减轻整个社会的经济负担。然而,临床上目前还是缺乏有效的治疗手段。中风后的病理过程复杂,多种因素参与并最终导致神经细胞死亡。过度激活谷氨酸受体的一类亚型-N-methyl-D-Aspartate(NMDA)受体而引发 With the aging of the society, ischemic stroke has become a major cause of disability and death in the world. The death of nerve cells after a stroke is a progressive and long-term process, and the study of its mechanism contributes to effective stroke treatment, which can not only relieve personal pain, but also reduce the economic burden on the entire society. However, the current clinical treatment is still lack of effective means. After the stroke pathological process is complicated, many factors involved and eventually lead to nerve cell death. Overexpression of glutamate receptor a subtype of N-methyl-D-Aspartate (NMDA) receptor and trigger