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肿节风是我国特有的抗癌草药,在临床上它对消化道恶性肿瘤已显示了良好的疗效,但是,由于药理模型问题没有很好解决,影响了其抗癌有效成分的分离及疗效的进一步提高。我们用体外法观察比较了肿节风的直接杀瘤作用,并通过动物接种进行了验证(半体内法)。初步看来,肿节风注射液在试管内对L615细胞具有一定的直接杀伤作用;而且经适当浓度肿节风注射液处理过的L615细胞(即肿节风L615瘤苗),当再接种于615小鼠后,绝大多数动物并不发病。表明肿节风注射液的体外处理确能使L615细胞灭能。现将实验结果小结汇报如下:
The swollen wind is a unique anti-cancer herb in China. It has been shown to have good curative effect on malignant tumors of the digestive tract in clinical practice. However, because the pharmacological model problem is not well resolved, it affects the isolation and efficacy of its anti-cancer effective components. Further improve. We compared the direct tumoricidal effect of tuophobilis with an in vitro method and verified it by animal vaccination (half-body method). Initially, Tuojiefeng injection has a certain direct killing effect on L615 cells in vitro; and L615 cells treated with a suitable concentration of Tuojiefeng injection (ie, Tumorous L615 tumor vaccine) when re-inoculated After 615 mice, the vast majority of animals did not develop the disease. It is shown that the treatment of Tuojiefeng injection can effectively deactivate L615 cells. The summary of the experimental results is now reported as follows: