硝硫氰胺在临床试用中已获得比锑剂疗效高,付作用小的满意结果。但是,部分病人服药后出现轻度中枢神经系统症状和黄疸。为了查明黄疸的发病机理,我们就硝硫氰胺对实验动物肝脏损害进行了病理形态学观察。 Nitrothiocyanamide has achieved higher efficacy than expectorant in clinical trials, with little satisfactory results. However, some patients had mild central nervous system symptoms and jaundice after taking the drug. In order to identify the pathogenesis of jaundice, we performed pathomorphological observations of nitrosamine-induced liver damage in experimental animals.