严重肝病和(或)广泛门静脉-体循环分流患者无明显肝性脑病的临床症状或体征,但出现注意力、警惕性、综合分析能力等神经认知功能损害时,称为轻微肝性脑病(minimal hepatic encephalopathy,MHE)。部分MHE患者可在短时间内发展成显性肝性脑病[1]。由于临床上很难区别West-Haven分级1级肝性脑病和MHE,因此国际肝性脑病和氮代谢 Patients with severe liver disease and / or extensive portal venous-circulatory shunting have no clinical signs or symptoms of hepatic encephalopathy, but are associated with neurocognitive impairment such as attention, vigilance, and comprehensive analysis, and are referred to as minimal hepatic encephalopathy hepatic encephalopathy, MHE). Some patients with MHE can develop into dominant hepatic encephalopathy in a short time [1]. Because it is clinically difficult to distinguish West-Haven grade 1 hepatic encephalopathy and MHE, international hepatic encephalopathy and nitrogen metabolism