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目的初步探讨踝臂血压指数(ABI)对于糖尿病伴发急性缺血性脑血管病的预测价值。方法按照临床表现1∶3配对设计的原则,连续收集本院2010年10月～2012年10月神经内科因脑梗死住院的患者(45～85岁),分为糖尿病伴有急性脑梗死患者组(实验组,DMP组)、糖尿病组(配对对照组,NDMP组),统计其一般临床资料和不同时间段的ABI值,采用相关回归分析探讨ABI与糖尿病患者并发急性缺血性脑血管病的关系。结果 (1)共选取到168名患者,其中DMP组42例(男23例,女19例),NDMP组126例(男72例,女54例),两组患者在一般的心脑血管病危险因素上无明显差异,具有可比性(P=0.482>0.05);(2)急性期DMP组与NDMP组相比ABI值差异显著,DMP组患者的ABI值明显下降(P=0.019<0.05);(3)经治疗后复测患者的ABI值,发现ABI值明显增加(P=0.006<0.01);(4)相关分析显示,ABI<0.90时与糖尿病患者发生急性脑梗死的相关系数OR=2.08(95%CI 1.40～2.84,P=0.001<0.01)。其与急性脑梗死的发生呈正相关。结论 ABI检测操作简单,可以作为简易识别糖尿病伴发急性脑梗死的预测指标。
Objective To investigate the predictive value of ankle-brachial blood pressure index (ABI) for diabetic patients with acute ischemic cerebrovascular disease. Methods According to the clinical manifestations of 1: 3 matching design, consecutive patients (45-85 years old) with cerebral infarction hospitalized from October 2010 to October 2012 in our hospital were divided into diabetic patients with acute cerebral infarction (Experimental group, DMP group), diabetic group (matched control group and NDMP group). The general clinical data and ABI values of different time periods were statistically analyzed. Correlation analysis was used to explore the relationship between ABI and diabetic patients with acute ischemic cerebrovascular disease relationship. Results (1) A total of 168 patients were selected, including 42 cases in DMP group (23 males and 19 females), 126 cases in NDMP group (72 males and 54 females) (P = 0.482> 0.05); (2) There was significant difference in ABI between DMP group and NDMP group in acute phase, and the ABI value in DMP group was significantly decreased (P = 0.019 <0.05) ; (3) After treatment, the ABI value of the patients in the retesting group was significantly increased (P = 0.006 <0.01); (4) The correlation analysis showed that the correlation coefficient between the ABI <0.90 and the diabetes patients with acute cerebral infarction OR = 2.08 (95% CI 1.40-2.84, P = 0.001 <0.01). It has a positive correlation with the occurrence of acute cerebral infarction. Conclusion The ABI detection is simple and can be used as a simple predictor of diabetes with acute cerebral infarction.