目的:提高前列腺癌(PCa)的诊断水平。方法:回顾了60例经穿刺活检确诊PCa患者的临床资料。结果:60例PCa患者中,血清T-PSA含量、F-PSA含量、F/T分别与PCa Gleason分级、临床分期均呈正相关,F/T与PCa Gleason分级、临床分期均无显著相关。结论:PCa患者的血清T-PSA、F-PSA和PSAD与Gleason分级和临床分期存在相关,提示可能通过检测血清T-PSA、F-PSA和PSAD预测PCa恶性程度及预后,有利于PCa的筛查及制定合理的治疗方案。 Objective: To improve the diagnosis of prostate cancer (PCa). Methods: The clinical data of 60 patients diagnosed PCa by biopsy were retrospectively reviewed. Results: Serum T-PSA content, F-PSA content and F / T were positively correlated with PCa Gleason grade and clinical stage in PCa patients. There was no significant correlation between F / T and PCa Gleason grade and clinical stage. CONCLUSIONS: Serum T-PSA, F-PSA and PSAD in patients with PCa correlate with Gleason classification and clinical stage, suggesting that PCa screening may be useful in predicting PCa malignancy and prognosis by detecting serum T-PSA, F-PSA and PSAD Check and develop a reasonable treatment plan.