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吖啶Ⅲ治疗毛细胞白血病2例取得了明显的近期及远期疗效。2例老年病人男女各1,经临床,化验,骨髓检查,骨髓、肝、脾活检,纸泳和电镜检查证实患有毛细胞白血病,并作了染色体组型检查。男病人有巨脾(xy 线=28 cm,AB=25 cm,Mn=10 cm)周围血毛细胞占72%。ⅠgM、ⅠgG 及 ES 很高,独用吖啶Ⅲ10天脾即明显缩小,后并用激素4个月后脾缩至8cm Mn 线缩至11 cm(脐左)。全血细胞减少,恢复正常。IG、ESR 及毛细胞减低。女病人脾原为8 cm 经2个月缩至完全不可触及,其它情况同前例。2例均属 Jansens 分级第3级病人,治疗后各自生存了6年及3年多。
Acridine III treatment of hairy cell leukemia in 2 cases achieved significant short-term and long-term efficacy. There were 2 male and 1 female patients in the 2 elderly patients, who had hair cell leukemia confirmed by clinical examination, bone marrow examination, bone marrow, liver and spleen biopsy, paper swimming and electron microscopy. Male patients with giant spleen (xy line = 28 cm, AB = 25 cm, Mn = 10 cm) around the blood cells accounted for 72%. ⅠgM, ⅠgG and ES are very high. Only acridine Ⅲ10 days spleen is significantly reduced, and after 4 months with hormones spleen shrink to 8cm Mn line reduced to 11 cm (navel left). Pancytopenia, returned to normal. IG, ESR and hair cell loss. Female patients with spleen was 8 cm by 2 months reduced to completely unreachable, the other cases with the previous case. 2 cases were all Jansens grade 3 patients, surviving for 6 years and 3 years respectively after treatment.