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目的了解我院药品不良反应(ADR)发生的规律与特点。方法收集我院2009年各科室上报的ADR报告33例,按患者的性别、年龄、给药途径、ADR因果关系、ADR类型及临床表现等方面进行统计、分析。结果33例ADR报告中,41～60岁患者发生率最高,占45.45%:静脉给药途径ADR发生率最高,占96.97%;抗菌药物ADR发生率最高,占60.61%;最常见的ADR临床表现为皮肤及其附件损害,占60.61%。结论临床加强合理应用抗菌药物和静脉注射药物,减少ADR的发生。
Objective To understand the rules and characteristics of adverse drug reaction (ADR) in our hospital. Methods A total of 33 ADR cases reported in our hospital in 2009 were collected and analyzed according to their gender, age, route of administration, cause and effect of ADR, type of ADR and clinical manifestations. Results Among 33 ADR cases, the highest incidence rate was 41.41% (45.45%). The incidence of ADR was the highest in intravenous route (96.97%), and the highest incidence rate of ADR was in antimicrobial drug (60.61%). The most common clinical manifestations of ADR Damage to the skin and its accessories, accounting for 60.61%. Conclusion Clinical application of antimicrobial agents and intravenous drugs should be strengthened to reduce the occurrence of ADR.