性激素结合球蛋白(SHBG)是在肝脏合成,是睾酮的主要载体蛋白,其次是雌二醇的载体蛋白。复合口服避孕药(OC)对SHBG最后的作用取决于雌、孕激素的剂量和类型及表达雌、雄激素的平衡。皮质类固醇结合球蛋白(CBG)也是在肝脏合成,仅由雌激素所诱发,故可用CBG升高量测量OCs雌激素作用的程度。作者对左旋18-甲基炔诺酮(LNG)单相和三相制剂、炔诺酮(NET)单相制 Sex hormone binding globulin (SHBG) is synthesized in the liver, is the main carrier protein testosterone, followed by estradiol carrier protein. The final effect of compound oral contraceptives (OCs) on SHBG depends on the dosage and type of estrogen and progesterone and the balance of estrogen and androgen expression. Corticosteroid-binding globulin (CBG) is also synthesized in the liver, induced only by estrogen, it can be used to measure the level of elevated CBG estrogen OCs extent. The author of the single-phase and three-phase preparation of levonor 18-norgestrel (LNG), single-phase norethindrone (NET)